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Image Search Results
Journal: Journal of Radiation Research
Article Title: Low-dose energetic protons induce adaptive and bystander effects that protect human cells against DNA damage caused by a subsequent exposure to energetic iron ions
doi: 10.1093/jrr/rrv005
Figure Lengend Snippet: Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human fibroblast cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.
Article Snippet: Apparently
Techniques: Irradiation
Journal: PLoS ONE
Article Title: Gamma Irradiation Does Not Induce Detectable Changes in DNA Methylation Directly following Exposure of Human Cells
doi: 10.1371/journal.pone.0044858
Figure Lengend Snippet: The Figure shows several randomly selected Signalmap snapshots of the microarray signals (green) for chromosomes 1, 3, 11, 19 and the X chromosome after the indicated treatments and recovery times. Above the treatment description are the CpG islands (indicated in black). A. Signalmap snapshots of HBEC (human bronchial epithelial cells) with the treatments 0 days, 0 Gray; 0 days, 4 Gray; 7 days, 0 Gray; 7 days, 0.1 Gray; 7 days, 1 Gray; 7 days, 4 Gray. B. Signalmap snapshots of HFB (human fibroblasts) with the treatments 0 days, 10 Gray; 7 days, 0 Gray; 7 days, 0.1 Gray; 7 days, 1 Gray; 7 days, 4 Gray; 7 days, 10 Gray.
Article Snippet:
Techniques: Microarray